Yori Endo
MB, BChir, MPhil, BSc
Yori Endo
MB, BChir, MPhil, BSc
About me
Dr. Yori Endo is an Instructor in the Department of Surgery, Division of Plastic and Reconstructive Surgery, Brigham and Women’s Hospital, Harvard Medical School. Research interests include muscle regeneration, aging, and tissue engineering.
ISCN 2022 Speaker Highlight - Dr. Yori Endo
The Effects of Exercise On Aged Skeletal Muscle
Yori Endo, MB, BChir, MPhil, BSc
We have found that physiological responses of skeletal muscles to exercise as reflected in muscle force / fatigue as well as running performance decline with aging. However, exercise has been shown to be effective in protecting and/or maintaining muscle functions in the elderly. The mechanism underlying this, however, has been unclear and it did not seem to relate to metabolic responses to exercise as seen in younger muscle. Our late RNA sequencing study has uncovered that there were significant changes in the gene expression of the components of glutaminergic transmission. As the presence, as well as the role of glutaminergic transmission at NMJs, are unknown, I will be exploring this angle in my future studies and I hope to incorporate some of the results by the conference.